Sunday, November 13th, 2022
4:00 pm - 5:30 pm Arrival and Registration
5:30 pm – 6:30 pm Welcome Reception (Pisgah & Pilot)
6:30 pm - 7:30 pm Dinner (Pisgah & Pilot)
7:45 pm – 7:55 pm Welcome and Opening Remarks (Mitchell & Roan)
Jamie Sturgill, University of Kentucky
8:00 pm – 9:00 pm Keynote Presentation
Alex Toker, Ph.D., Harvard Medical School and Beth Israel Deaconess Medical Center
9:00 pm – 11:00 pm Social Time and Preliminary Poster Viewing (Pisgah & Pilot)
Monday, November 14th, 2022
8:00 am - 9:00 am Breakfast (Pisgah & Pilot)
9:00 am – 10:15 am Oral Session I (Mitchell & Roan) Lipids in Cancer
Session Chairs: Prasanna Iyer and Stocko Stamatikos
9:00 am IRF8 regulates the intrinsic ferroptosis to control tumor cell vulnerability to cytotoxic T lymphocytes. Dakota Poschel. Medical College of Georgia.
9:15 am Cellular glycosphingolipid imbalance modulates EMT in cancer cells. Laura Clark. Virginia Commonwealth University.
9:30 am INPP4B signaling controls cancer progression through the regulation of lysosomal functions. Lenny Salmena. University of Toronto.
9:45 am Co-targeting Glucosylceramide Synthase and Serine Palmitoyl Transferase for Colon Cancer Therapy. Allie Strauss. Virginia Commonwealth University.
10:00 am Understanding the function and mechanism of mammalian START-like PITPNC1 in relation to cancer. Adrija Pathak. Texas A&M University.
10:15 am – 10:30 am Break
10:30 am – 11:30 pm Oral Session II (Mitchell & Roan) Lipids in Diabetes and Metabolic Disease
Session Chairs: Salim El-Amouri and David Montefusco
10:30 am Spatial metabolomics of endotoxin-induced kidney injury in diabetes. Tom DeLuca. Indiana University
10:45 am Conditional Reduction of iPLA2β in Macrophages Protects from Type 1 Diabetes Pathogenesis and Incidence in NOD mice. Abdulaziz Almutairi. University of Alabama at Birmingham.
11:00 am Inhibition of ceramide rich platform formation via anti-ceramide immunotherapy for diabetic retinopathy. Arjun Singh. Memorial Sloan Kettering Cancer Center.
11:15 am T Lymphocytes with Reduced iPLA2β Expression Delays Type I Diabetes Development in NOD Female Mice. Tayleur White. University of Alabama at Birmingham.
11:30 am – 12:30 pm Keynote Presentation
Alyssa Hasty, Ph.D., Vanderbilt University School of Medicine
12:30 pm – 1:30 pm Lunch (Pisgah & Pilot)
1:30 pm – 4:00 pm Free time
4:00 pm - 6:00 pm Poster Session (Pisgah & Pilot) and Cocktail Hour
Poster Session Chairs: Lenny Salmena and Lokman Hossen
6:00 pm – 6:15 pm Awards ceremony (Mitchell & Roan)
6:15 pm – 6:30 pm Presentation of the Lina Obeid Young Scientist Award
Ashley Cowart, Ph.D., Virginia Commonwealth University
6:30 pm – 7:00 pm Lina Obeid Young Scientist Award Lecture
7:00 pm – 8:00 pm SERLC Banquet at the Expo Center
8:00 pm – 11:00 pm Live Bluegrass Entertainment and Square Dancing at the Expo Center
Tuesday, November 15th, 2022
8:00 am - 9:00 am Breakfast (Pisgah & Pilot)
9:00 am – 10:15 am Oral Session III (Mitchell & Roan) Lipids in Hepatic Disease
Session chairs: Arjun Singh and Yao Zhang
9:00 am Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic fatty liver disease. Ryan Brown. Virginia Commonwealth University.
9:15 am Regulation of nSMase2 in AML-12 cells, a novel model of hepatic steatosis. Salim El-Amouri. University of Kentucky
9:30 am Novel role for Serine Palmitoyltransferase 3 (SPTLC3) in liver mitochondrial dysfunction. Maryam Jamil. Virginia Commonwealth University.
9:45 am Investigating how Signaling Lipids Regulate the Structure and Function of Liver Receptor Homolog-1. James Poland. Vanderbilt University.
10:00 am Atypical SPTLC3-Generated Sphingolipids as Regulators of Hepatic Glucose Production. David Montefusco. Virginia Commonwealth University.
10:15 am – 10:45 am Break - please make sure you are checked out of the hotel at this time.
10:45 am – 12:00 pm Oral Session IV (Mitchell & Roan) Lipids in Inflammation
Session chairs: Ryan Brown and Tom DeLuca
10:45 am Generation of exhausted monocytes memory and underlying mechanisms. Yajun Wu. Virginia Tech
11:00 am Ceramide as a novel biomarker in acute respiratory distress syndrome. Luke McKinney. University of Kentucky.
11:15 am Phosphatidylinositol-4-Phosphate regulates the formation of dense granules in Toxoplasma gondii. Angela Arabiotorre. Texas A&M University
11:30 am Sphingolipids in exhaled breath condensate of patients with pulmonary disease. Alex Williams. University of Kentucky
11:45 am Ceramide Synthase 6 Regulates Mouse Brain Metabolome. Madeline Hall. University of North Carolina.
12:00 pm – 12:30 pm Closing Remarks and SERLC Business meeting to plan for 2023 Conference.
12:30 pm – 1:30 pm Lunch (Pisgah & Pilot)
1:30 pm 56th SERLC adjournedT
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